Description
Product Characteristics: This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],PUMH2, PUML2,Cell Biology & Developmental Biology,Embryonic Stem Cells,Epigenetics & Nuclear Signaling,Germline Stem Cells,RNA Binding,Stem Cells,PUM2
Target Information: Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts (By similarity)